Wolves included trialist Balazs Molnar in their starting line-up at Prenton Park and the Hungarian international midfielder set up Denes Rosa for the opening goal after just minutes.
The hosts drew level just ten minutes later however through Chris Greenacre.
Wolves Draw At Tranmere
Wolves took a 2-1 lead 17 minutes into the second half with a Carl Cort header but Tranmere drew level again from a Jason McAteer free kick.
Tranmere: Ward, Stockdale, Tremarco, McCready (Goodison 79), McLaren (McAteer 71), Sherriff, Shuker (M. Jones 79), Mullin, Taylor (Zola 71), Greenacre, Ellison.
Tranmere: Ward, Stockdale, Tremarco, McCready (Goodison 79), McLaren (McAteer 71), Sherriff, Shuker (M. Jones 79), Mullin, Taylor (Zola 71), Greenacre, Ellison.
Wolves: Oakes, Little, Clyde, Molnar (Clarke 85), Craddock, Edwards, Rosa, M. Davies (McNamara 83), Cort, Frankowski, D. Jones (Finkler 62) (Gleeson 83).