Wolves are five points adrift of safety after last Saturday's 3-2 home defeat against Bolton.
But they now face Blackpool, Blackburn, Birmingham, West Brom and Wigan in five of their next six games in addition to sixth placed Sunderland.
McCarthy said: "We are getting good at taking positives out of defeats and I am sick of it. It is wearing a bit thin. We've played well enough in all the games recently.
"We always take the positives out of any game but it is time to get three points. In games when you are playing teams, like we've got in the next six or seven games, you've got to get points.
"It is it a defining period up to Christmas. With the position we are in now, we've got to get results and wins and we have to get them quickly. We can't wait any longer for them."
Source: PA
Source: PA