Stuart Pearce's side will take on the Poles at Wolves' home ground on Tuesday, March 25th with a 7pm kick-off time.
"Interest in the Under-21s is extremely high at the moment and that's shown by us playing in front of sell-out crowds in our last two games in Milton Keynes and Southampton. We'd be delighted to see a full house at Molineux next month, it's a stadium I always enjoy visiting with a passionate crowd," Pearce told the FA's official website.