Doyle suffered medial knee ligament damage during the Republic of Ireland's 2-1 European Championship win over Macedonia on Saturday. Republic boss Giovanni Trapattoni claimed the 27-year-old would be out for between one and two months, which could see him miss Wolves' final eight games of the campaign.
Berra said: "It's a massive blow for us, he's a top player, he does a great job for us up front."
He added: "But we've got good strikers on the bench in Sylvan Ebanks-Blake and Steven Fletcher, who have come in this season and done well and scored goals for us.
"So we won't be getting down about that, we'll move on."
Wolves, who are currently 18th in the Premier League with 32 points, travel to Newcastle on Saturday looking to climb out of the bottom three in what is one of the tightest relegation battles in Premier League history.
Berra said: "I think it's two points between six or eight teams and we've actually got better points this season than at the same point last season, so it shows our improvement.
"We're a better team now, we play better football overall.
"As players, as individuals, we've improved. So we'll go onwards and upwards.
"We're four games unbeaten and we'll be going away to Newcastle in high spirits."
Source: PA
Source: PA